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Cassiopeia

Build Cassiopeia Mid

Runes, items & skill order

Mage

Patch 16.20

Customize your build
Role
Win rate45.19%
Pick rate1.04%
Ban rate0.93%
TierD
OPMetaLoL›Champions›Cassiopeia

All servers · Patch 16.20 · 2026-10-13 01:08 UTC · Data sources

Build Cassiopeia Mid

Keystone rune

Deathfire Touch

Sorcery + Precision

Skill priority

E → Q → W

View the level-by-level order

Compare win rates by rank

Choose a rank to load its own build and statistics. Win rates describe different player samples; they do not measure how easy a rank is.

RankWin rateCore build sample
Emerald+48.24%2,334
All ranks46.27%7,160
Iron44.78%99
Bronze44.43%497
Silver45.70%1,099
Gold45.19%1,447
Platinum——
Emerald47.16%1,279
Diamond48.86%638
Master50.41%361
Grandmaster46.34%39
Challenger——
Cassiopeia Runes Cassiopeia Mid Build
45.19% WR
Sorcery Primary
Precision Secondary
Stat Shards
Offense
Adaptive Force Attack Speed Ability Haste
Adaptive Force
Flex
Adaptive Force Movement Speed Health Scaling
Adaptive Force
Defense
Health Tenacity and Slow Resist Health Scaling
Health Scaling
Summoner Spells 45.19%
Flash Flash
Teleport Teleport

Items

Starting items
item 1056
item 2003
45.18% WR 5,531 matches
Most popular starting combination
Core items
item 6657
→
item 3040
→
item 3116
→
item 3009
52.59% WR 1,447 matches
Popular core combination
Fourth item options
item 3157
Zhonya's Hourglass 52.87% WR 715 matches
item 6653
Liandry's Torment 53.56% WR 618 matches
item 3089
Rabadon's Deathcap 58.08% WR 427 matches
item 3116
Rylai's Crystal Scepter 50.00% WR 344 matches
item 3135
Void Staff 53.92% WR 102 matches
Fifth item options
item 3089
Rabadon's Deathcap 52.82% WR 195 matches
item 3157
Zhonya's Hourglass 48.26% WR 172 matches
item 3135
Void Staff 61.33% WR 75 matches
item 6653
Liandry's Torment 55.74% WR 61 matches
item 3116
Rylai's Crystal Scepter 55.00% WR 40 matches
Sixth item options
item 3135
Void Staff 80.00% WR 5 matches
item 3089
Rabadon's Deathcap 25.00% WR 4 matches
item 4629
Cosmic Drive 66.67% WR 3 matches
item 3157
Zhonya's Hourglass 100.00% WR 2 matches
item 6653
Liandry's Torment 50.00% WR 2 matches

Skill priority

E
E
→
Q
Q
→
W
W
45.19% WR

Skill order

Most popular ability leveling order · source levels 1–15

Levels 1–5

Ability12345
Noxious BlastQ ·Q···
MiasmaW ··W··
Twin FangE E··EE
Petrifying GazeR ·····

Levels 6–10

Ability678910
Noxious BlastQ ··Q·Q
MiasmaW ·····
Twin FangE ·E·E·
Petrifying GazeR R····

Levels 11–15

Ability1112131415
Noxious BlastQ ·QQ··
MiasmaW ···WW
Twin FangE ·····
Petrifying GazeR R····
Q
Q Noxious Blast
2
8
10
12
13
W
W Miasma
3
14
15
E
E Twin Fang
1
4
5
7
9
R
R Petrifying Gaze
6
11
passive
P Serpentine Grace

Champion win rate against each opponent, for the selected role and rank. Small samples are less reliable.

Cassiopeia Mid build guide: runes, items and skill order

This Cassiopeia Mid build covers League of Legends patch 16.20. Compare the selected runes, starting items and core purchases before the match, then adapt your later purchases to enemy damage and defenses. The source recommendations use the Gold filter across all servers.

For Cassiopeia runes, this setup uses Deathfire Touch with Precision as the secondary path. Check the highlighted stat shards as well: they are part of the rune page, not extra items. Hover or tap a rune to read its effect before deciding whether it suits your matchup.

The displayed Cassiopeia skill order starts with E and prioritizes E → Q → W. The level-by-level grid covers the first 15 levels supplied by the source. Follow that sequence as a reference while accounting for what your lane or team needs. Item win rates describe completed purchases and should be read alongside their game counts.

Which items should you build on Cassiopeia Mid?

The most popular core items in this Cassiopeia Mid build are Rod of Ages → Seraph's Embrace → Rylai's Crystal Scepter. Check starting items and boots separately, then compare later item options against the enemy team. This is a reference for patch 16.20, not a fixed purchase order for every match.

Which runes should you choose for Cassiopeia Mid?

For the selected Gold rank filter, the rune page uses Deathfire Touch with Precision. Review each rune tooltip and the selected stat shards before entering champion select.

How do you compare Cassiopeia builds by rank?

Use the rank selector to view a separate build and win rate for Iron, Bronze, Silver, Gold, Platinum, Emerald, Diamond, Master, Grandmaster or Challenger. Keep the same role when comparing. A small sample is less reliable, and a higher win rate alone does not prove a better build.

How this build works

Rune choice

This setup pairs Sorcery with Precision and uses Deathfire Touch as its keystone. The highlighted runes and shards belong to this imported setup; inspect an icon to read its effect.

Core purchases

The most popular core combination in the source is Rod of Ages → Seraph's Embrace → Rylai's Crystal Scepter. Treat it as a starting point: choose defensive or penetration options for the opponents you are facing.

Read the sample

The core combination has an observed win rate of 52.59% across 1,447 games. These are games that reached this purchase combination, not all games played by the champion. A completed build can appear stronger because winning players can afford more items.

How we select and update builds →

How to play Cassiopeia: combos, tips and builds

Learn Cassiopeia abilities and prepare your first games. Find builds for each supported role.

Read the guide

About Cassiopeia

Cassiopeia is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia now slithers under the veil of night, petrifying her enemies with her baleful gaze.