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OPMETALOL · CHAMPION GUIDE

How to play Cassiopeia: combos, tips and builds

Learn the kit, practise the combos, and make better decisions in your next game.

01 / Cassiopeia

At a glance

Learn Cassiopeia abilities and prepare your first games. Find builds for each supported role.

4 active abilitiesCombos: 2Builds by role & rank

02

Strengths & weaknesses

Tools to play around

What can go wrong

  • Noxious BlastRead the effect and its conditions, then practise it alone. Build your sequence around the effect you can reliably reproduce.
  • Twin FangPractise the hit area and target conditions first. Do not spend the rest of your rotation automatically when the opening damage misses.
  • A completed combo is only useful when your position, resources and follow-up are safe.

03

Abilities & tips

Open an ability to read its effect and a practical use tip.

PSerpentine Grace

All Move Speed bonuses are more effective on Cassiopeia.

Use it well

Read the effect and its conditions, then practise it alone. Build your sequence around the effect you can reliably reproduce.

QNoxious Blast

Cassiopeia blasts an area with Poison after a brief delay, granting her increased Move Speed if she hits an enemy champion.

Use it well

Read the effect and its conditions, then practise it alone. Build your sequence around the effect you can reliably reproduce.

WMiasma

Cassiopeia releases several clouds of poison, slowing, grounding, and lightly damaging enemies that pass through them. Grounded enemies cannot use Movement abilities.

Use it well

Read the effect and its conditions, then practise it alone. Build your sequence around the effect you can reliably reproduce.

ETwin Fang

Cassiopeia lets loose an attack that deals increased damage to Poisoned targets and heals her for a percentage of the damage dealt. If the target dies from this attack, Cassiopeia regains Mana.

Use it well

Practise the hit area and target conditions first. Do not spend the rest of your rotation automatically when the opening damage misses.

RPetrifying Gaze

Cassiopeia releases a swirl of magical energy from her eyes, stunning any enemies in front of her that are facing her and slowing any others with their back turned.

Use it well

Use this control to create a follow-up window. Check the target’s defensive spells and your teammates’ range before committing.

Cassiopeia combos: execution and timing

AA = basic attack · EAA = empowered attack · 1/2/3 = cast stage. Follow the order, not instant key presses.

Recast practice: Noxious Blast

  1. Noxious BlastQ
  2. Twin FangE
  3. Twin FangE
  4. Twin FangE
  5. Twin FangE
  6. Noxious BlastQ

With Cassiopeia, start with Noxious Blast, then continue through Twin Fang → Twin Fang → Twin Fang → Twin Fang → Noxious Blast. Track the marks from Noxious Blast before following with Twin Fang. Compare a marked target with an unmarked one in practice.

Mistake to avoid : Do not assume the same damage, control or follow-up when the required indicator is missing.

Repeated spells may need a recast window or a cooldown; check that the next activation is actually available.

Recast practice: Noxious Blast

  1. Noxious BlastQ
  2. Twin FangE
  3. Twin FangE
  4. MiasmaW
  5. Twin FangE
  6. Twin FangE
  7. Noxious BlastQ
  8. Twin FangE

With Cassiopeia, start with Noxious Blast, then continue through Twin Fang → Twin Fang → Miasma → Twin Fang → Twin Fang → Noxious Blast → Twin Fang. Track the marks from Noxious Blast before following with Twin Fang. Compare a marked target with an unmarked one in practice.

Mistake to avoid : Do not assume the same damage, control or follow-up when the required indicator is missing.

Repeated spells may need a recast window or a cooldown; check that the next activation is actually available.

05

Game plan by role

Cassiopeia · Mid
Early game

Use the wave to control when trades happen. Keep a defensive option if the opposing jungler is missing, and avoid forcing a combo into a large enemy wave.

Mid game

Move after checking the wave, vision and who can follow. A useful roam should not cost several uncontested waves for no clear opportunity.

Teamfights

Fight from a position where you can repeat your useful spells. Look for an opening after enemy control is spent instead of entering first by habit.

Before your next fight, check: Noxious Blast · Petrifying Gaze · Combos

06

Matchup preparation

Compare opponents in the build for the role you are actually playing. Then check their key control, escape and defensive spells before choosing your trade.

07

Practice checklist

  1. Cast each ability alone and identify its range, target conditions and stopping point.
  2. Practise the first sequence slowly. Repeat it while moving, without skipping the conditions shown on its card.
  3. After each attempt, identify the spell you would still have available to defend or retreat.

08

Cassiopeia · Builds & runes

Choose a role, then select your rank on the build page for runes, items, skill order and matchup statistics.