Rune choice
This setup pairs Inspiration with Domination and uses First Strike as its keystone. The highlighted runes and shards belong to this imported setup; inspect an icon to read its effect.

Runes, items & skill order
Patch 26.20
All servers · Patch 26.20 · 2026-10-14 01:54 UTC · Data sources
Choose a rank to load its own build and statistics. Win rates describe different player samples; they do not measure how easy a rank is.


First Strike
Flash
Teleport| Ability | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
| Q | Q | · | · | · | · |
| W | · | W | · | · | · |
| E | · | · | E | E | E |
| R | · | · | · | · | · |
| Ability | 6 | 7 | 8 | 9 | 10 |
|---|---|---|---|---|---|
| Q | · | · | · | · | · |
| W | · | · | W | · | W |
| E | · | E | · | E | · |
| R | R | · | · | · | · |
| Ability | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|
| Q | · | · | · | Q | Q |
| W | · | W | W | · | · |
| E | · | · | · | · | · |
| R | R | · | · | · | · |
Champion win rate against each opponent, for the selected role and rank. Small samples are less reliable.
Read the full Kassadin guide →
This Kassadin Mid build covers League of Legends patch 16.20. Compare the selected runes, starting items and core purchases before the match, then adapt your later purchases to enemy damage and defenses. The source recommendations use the All ranks filter across all servers.
For Kassadin runes, this setup uses First Strike with Domination as the secondary path. Check the highlighted stat shards as well: they are part of the rune page, not extra items. Hover or tap a rune to read its effect before deciding whether it suits your matchup.
The displayed Kassadin skill order starts with Q and prioritizes E → W → Q. The level-by-level grid covers the first 15 levels supplied by the source. Follow that sequence as a reference while accounting for what your lane or team needs. Item win rates describe completed purchases and should be read alongside their game counts.
The most popular core items in this Kassadin Mid build are Rod of Ages → Seraph's Embrace → Malignance. Check starting items and boots separately, then compare later item options against the enemy team. This is a reference for patch 26.20, not a fixed purchase order for every match.
For the selected All ranks rank filter, the rune page uses First Strike with Domination. Review each rune tooltip and the selected stat shards before entering champion select.
Use the rank selector to view a separate build and win rate for Iron, Bronze, Silver, Gold, Platinum, Emerald, Diamond, Master, Grandmaster or Challenger. Keep the same role when comparing. A small sample is less reliable, and a higher win rate alone does not prove a better build.
This setup pairs Inspiration with Domination and uses First Strike as its keystone. The highlighted runes and shards belong to this imported setup; inspect an icon to read its effect.
The most popular core combination in the source is Rod of Ages → Seraph's Embrace → Malignance. Treat it as a starting point: choose defensive or penetration options for the opponents you are facing.
The core combination has an observed win rate of 55.59% across 13,023 games. These are games that reached this purchase combination, not all games played by the champion. A completed build can appear stronger because winning players can afford more items.
Learn Kassadin abilities and prepare your first games. Find builds for each supported role.
Read the guideCutting a burning swath through the darkest places of the world, Kassadin knows his days are numbered. A widely traveled Shuriman guide and adventurer, he had chosen to raise a family among the peaceful southern tribes—until the day his village was consumed by the Void. He vowed vengeance, combining a number of arcane artifacts and forbidden technologies for the struggle ahead. Finally, Kassadin set out for the wastelands of Icathia, ready to face any monstrous Void-construct in his search for their self-proclaimed prophet, Malzahar.